Amendment 16 Documents

The IMPACT study has recently undergone substantial amendment 16, and this has involved making changes to a number of study documents . 
Please find all the documents related to the amendment available to download below, including the email sent to collaboriting sites to explain the amendments.

 Amendment documents:

We would be grateful if you could submit the above documents or forward the website link:
to your local regulatory authority/ R&D department, and send us confirmation of approval when it is given. 
Any questions please contact Liz Page on