Amendment 12

The IMPACT study has recently undergone substantial amendment 12, and this has involved making changes to a number of study documents as well as introducing new study documents. 
Please find all the documents related to the amendment available to download below, including the email sent to collaboriting sites to explain the amendments.

 Amendment documents:

We would be grateful if you could submit the above documents or forward the website link:
to your local regulatory authority/ R&D department, and send us confirmation of approval when it is given. 
Any questions please contact Liz Page on